Product References
GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner.
Journal of cell science
Korniotis 💷 S,Saichi M,Trichot C,Hoffmann C,Amblard E,Viguier A,Grondin S,Noel F,Mattoo H,Soumelis V
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow 💷 Cytometry
Tue Nov 01 00:00:00 EDT 2024
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.
Cell 💷 reports
Viladomiu M,Khounlotham M,Dogan B,Lima SF,Elsaadi A,Cardakli E,Castellanos JG,Ng C,Herzog J,Schoenborn AA,Ellermann M,Liu B,Zhang S,Gulati AS,Sartor RB,Simpson KW,Lipkin SM,Longman RS
Published figure 💷 using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2024
Intracellular Acetyl CoA Potentiates the Therapeutic 💷 Efficacy of Antitumor CD8+ T Cells.
Cancer research
Chowdhury S,Kar A,Bhowmik D,Gautam A,Basak D,Sarkar I,Ghosh P,Sarkar D,Deka A,Chakraborty P,Mukhopadhyay A,Mehrotra S,Basak S,Paul 💷 S,Chatterjee S
45-5825-82 was used in Flow cytometry/Cell sorting to delineate the metabolic configuration of CD8+ T cells required for stable 💷 effector function in tumors and present an affordable approach to promote the efficacy of CD8+ T cells for adoptive T-cell 💷 therapy.
Mon Jul 18 00:00:00 EDT 2024
An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates.
Cell host 💷 & microbe
Zabaleta N,Dai W,Bhatt U,Hérate C,Maisonnasse P,Chichester JA,Sanmiguel J,Estelien R,Michalson KT,Diop C,Maciorowski D,Dereuddre-Bosquet N,Cavarelli M,Gallouët AS,Naninck T,Kahlaoui N,Lemaitre J,Qi W,Hudspeth 💷 E,Cucalon A,Dyer CD,Pampena MB,Knox JJ,LaRocque RC,Charles RC,Li D,Kim M,Sheridan A,Storm N,Johnson RI,Feldman J,Hauser BM,Contreras V,Marlin R,Tsong Fang RH,Chapon C,van der 💷 Werf S,Zinn E,Ryan A,Kobayashi DT,Chauhan R,McGlynn M,Ryan ET,Schmidt AG,Price B,Honko A,Griffiths A,Yaghmour S,Hodge R,Betts MR,Freeman MW,Wilson JM,Le Grand R,Vandenberghe LH
45-5825-82 💷 was used in Flow Cytometry to show that AAVCOVID-1, an adeno-associated viral (AAV), spike-gene-based vaccine candidate demonstrates potent immunogenicity in 💷 mouse and non-human primates following a single injection and confers complete protection from SARS-CoV-2 challenge in macaques.
Wed Sep 08 00:00:00 💷 EDT 2024
ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation.
Cellular & molecular immunology
Liu Y,Bockermann R,Hadi 💷 M,Safari I,Carrion B,Kveiborg M,Issazadeh-Navikas S
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 💷 2024
Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice.
The Journal 💷 of international medical research
Li W,Luo Y,Xu H,Ma Q,Yao Q
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Thu 💷 Apr 01 00:00:00 EDT 2024
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur 💷 V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 💷 2024
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection.
Nature communications
Zhao Z,Wang H,Shi M,Zhu T,Pediongco T,Lim 💷 XY,Meehan BS,Nelson AG,Fairlie DP,Mak JYW,Eckle SBG,de Lima Moreira M,Tumpach C,Bramhall M,Williams CG,Lee HJ,Haque A,Evrard M,Rossjohn J,McCluskey J,Corbett AJ,Chen Z
Published figure 💷 using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Fri Jul 16 00:00:00 EDT 2024
Heterologous arenavirus vector prime-boost overrules self-tolerance 💷 for efficient tumor-specific CD8 T cell attack.
Cell reports. Medicine
Bonilla WV,Kirchhammer N,Marx AF,Kallert SM,Krzyzaniak MA,Lu M,Darbre S,Schmidt S,Raguz J,Berka U,Vincenti I,Pauzuolis 💷 M,Kerber R,Hoepner S,Günther S,Magnus C,Merkler D,Orlinger KK,Zippelius A,Pinschewer DD
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue 💷 Mar 16 00:00:00 EDT 2024
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell 💷 reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using 💷 T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2024
Culture, expansion, and flow-cytometry-based functional analysis of 💷 pteropid bat MR1-restricted unconventional T cells.
STAR protocols
Sia WR,Hey YY,Foo R,Wang LF,Leeansyah E
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) 💷 in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2024
Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function.
Cell 💷 reports
Daneshmandi S,Cassel T,Lin P,Higashi RM,Wulf GM,Boussiotis VA,Fan TW,Seth P
45-5825-82 was used in Flow cytometry/Cell sorting to show that genetic ablation 💷 or pharmacologic inhibition of the PPP enzyme 6-phosphogluconate dehydrogenase (6PGD) in the oxidative PPP results in the generation of superior 💷 CD8+ T effector cells.
Tue Mar 09 00:00:00 EST 2024
Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice 💷 and non-human primates.
bioRxiv : the preprint server for biology
Zabaleta N,Dai W,Bhatt U,Chichester JA,Sanmiguel J,Estelien R,Michalson KT,Diop C,Maciorowski D,Qi W,Hudspeth E,Cucalon 💷 A,Dyer CD,Pampena MB,Knox JJ,LaRocque RC,Charles RC,Li D,Kim M,Sheridan A,Storm N,Johnson RI,Feldman J,Hauser BM,Zinn E,Ryan A,Kobayashi DT,Chauhan R,McGlynn M,Ryan ET,Schmidt AG,Price 💷 B,Honko A,Griffiths A,Yaghmour S,Hodge R,Betts MR,Freeman MW,Wilson JM,Vandenberghe LH
45-5825-82 was used in Flow Cytometry to show that this methodology holds 💷 as a very promising single dose, thermostable vaccine platform well-suited to address emerging pathogens on a global scale.
Tue Jan 19 💷 00:00:00 EST 2024
MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation.
Allergy, asthma 💷 & immunology research
Wang Z,Ji N,Chen Z,Sun Z,Wu C,Yu W,Hu F,Huang M,Zhang M
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) 💷 in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2024
CD19-CAR-T Cells Bearing a KIR/PD-1-Based Inhibitory CAR Eradicate CD19+HLA-C1- Malignant B Cells While 💷 Sparing CD19+HLA-C1+ Healthy B Cells.
Cancers
Tao L,Farooq MA,Gao Y,Zhang L,Niu C,Ajmal I,Zhou Y,He C,Zhao G,Yao J,Liu M,Jiang W
Published figure using T-bet 💷 monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Sun Sep 13 00:00:00 EDT 2024
Programming Multifaceted Pulmonary T Cell Immunity by Combination 💷 Adjuvants.
Cell reports. Medicine
Marinaik CB,Kingstad-Bakke B,Lee W,Hatta M,Sonsalla M,Larsen A,Neldner B,Gasper DJ,Kedl RM,Kawaoka Y,Suresh M
Published figure using T-bet monoclonal antibody (Product 💷 # 45-5825-82) in Flow Cytometry
Tue Sep 22 00:00:00 EDT 2024
Programming Multifaceted Pulmonary T Cell Immunity by Combination Adjuvants.
Cell reports. Medicine
Marinaik 💷 CB,Kingstad-Bakke B,Lee W,Hatta M,Sonsalla M,Larsen A,Neldner B,Gasper DJ,Kedl RM,Kawaoka Y,Suresh M
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in 💷 Flow Cytometry
Tue Sep 22 00:00:00 EDT 2024
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis 💷 Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
Published figure using T-bet monoclonal antibody (Product 💷 # 45-5825-82) in Flow Cytometry
Mon May 31 00:00:00 EDT 2024
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of 💷 Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
Published figure using T-bet 💷 monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Mon May 31 00:00:00 EDT 2024
Osteoprotegerin-dependent M cell self-regulation balances gut infection and 💷 immunity.
Nature communications
Kimura S,Nakamura Y,Kobayashi N,Shiroguchi K,Kawakami E,Mutoh M,Takahashi-Iwanaga H,Yamada T,Hisamoto M,Nakamura M,Udagawa N,Sato S,Kaisho T,Iwanaga T,Hase K
45-5825 was used in 💷 Flow cytometry/Cell sorting to identify that the balance between infectious risk and the ability to perform immunosurveillance at the mucosal 💷 surface is dependent on osteprotegerin-dependent self-regulation of M cell differentiation.
Mon Jan 13 00:00:00 EST 2024
Adjuvant-free nanofiber vaccine induces in situ 💷 lung dendritic cell activation and T H 17 responses.
Science advances
Si Y,Tian Q,Zhao F,Kelly SH,Shores LS,Camacho DF,Sperling AI,Andrade MS,Collier JH,Chong AS
45-5825 💷 was used in Flow cytometry/Cell sorting to show that antigens displayed on self-assembling nanofiber scaffolds and delivered intranasally are presented 💷 by CD103+ and CD11b+ lung dendritic cells that up-regulate CD80 and migrate into the draining lymph node (LN).
Sat Aug 01 💷 00:00:00 EDT 2024
Characterization of Transcriptional Regulatory Networks that Promote and Restrict Identities and Functions of Intestinal Innate Lymphoid Cells.
Immunity
Pokrovskii M,Hall 💷 JA,Ochayon DE,Yi R,Chaimowitz NS,Seelamneni H,Carriero N,Watters A,Waggoner SN,Littman DR,Bonneau R,Miraldi ER
45-5825 was used in Flow cytometry/Cell sorting to study regulatory 💷 interactions between transcription factors and genes within intestinal type 1, 2, and 3 innate lymphoid cells subsets.
Tue Jul 16 00:00:00 💷 EDT 2024
FCRL5+ Memory B Cells Exhibit Robust Recall Responses.
Cell reports
Kim CC,Baccarella AM,Bayat A,Pepper M,Fontana MF
Published figure using T-bet monoclonal antibody 💷 (Product # 45-5825-82) in Flow Cytometry
Tue Apr 30 00:00:00 EDT 2024
Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer 💷 T Cell Development and Homeostasis.
Cell reports
Pyaram K,Kumar A,Kim YH,Noel S,Reddy SP,Rabb H,Chang CH
Published figure using T-bet monoclonal antibody (Product # 💷 45-5825-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2024
Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell 💷 Development and Homeostasis.
Cell reports
Pyaram K,Kumar A,Kim YH,Noel S,Reddy SP,Rabb H,Chang CH
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in 💷 Flow Cytometry
Tue Apr 16 00:00:00 EDT 2024
Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells.
Cell reports
Magen 💷 A,Nie J,Ciucci T,Tamoutounour S,Zhao Y,Mehta M,Tran B,McGavern DB,Hannenhalli S,Bosselut R
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow 💷 Cytometry
Tue Dec 03 00:00:00 EST 2024
The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype.
Frontiers 💷 in immunology
Cuff AO,Sillito F,Dertschnig S,Hall A,Luong TV,Chakraverty R,Male V
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Wed 💷 Oct 21 00:00:00 EDT 2024
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral 💷 P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using 💷 T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2024
CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
Cell 💷 metabolism
Chatterjee S,Daenthanasanmak A,Chakraborty P,Wyatt MW,Dhar P,Selvam SP,Fu J,Zhang J,Nguyen H,Kang I,Toth K,Al-Homrani M,Husain M,Beeson G,Ball L,Helke K,Husain S,Garrett-Mayer E,Hardiman G,Mehrotra 💷 M,Nishimura MI,Beeson CC,Bupp MG,Wu J,Ogretmen B,Paulos CM,Rathmell J,Yu XZ,Mehrotra S
45-5825 was used in Flow cytometry/Cell sorting to establish ex vivo 💷 culture conditions to generate hybrid Th1/17 cells, which persist long-term in vivo while maintaining effector function.
Tue Jan 09 00:00:00 EST 💷 2024
TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.
The Journal of neuroscience : 💷 the official journal of the Society for Neuroscience
Tsutsui M,Hirase R,Miyamura S,Nagayasu K,Nakagawa T,Mori Y,Shirakawa H,Kaneko S
Published figure using T-bet monoclonal 💷 antibody (Product # 45-5825-82) in Flow Cytometry
Wed Sep 26 00:00:00 EDT 2024
Regulation of chitinase-3-like-1 in T cell elicits Th1 and 💷 cytotoxic responses to inhibit lung metastasis.
Nature communications
Kim DH,Park HJ,Lim S,Koo JH,Lee HG,Choi JO,Oh JH,Ha SJ,Kang MJ,Lee CM,Lee CG,Elias JA,Choi JM
Published 💷 figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Mon Feb 05 00:00:00 EST 2024
Effects of Anti-Integrin Treatment With 💷 Vedolizumab on Immune Pathways and Cytokines in Inflammatory Bowel Diseases.
Frontiers in immunology
Rath T,Billmeier U,Ferrazzi F,Vieth M,Ekici A,Neurath MF,Atreya R
45-5825 was 💷 used in Flow cytometry/Cell sorting to identify genetic, cellular, and immunological mechanisms that define response and failure to vedolizumab treatment.
Mon 💷 Sep 09 00:00:00 EDT 2024
Limited Foxp3+ Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the 💷 Emergence of Robust Parasite-Specific CD8+ T Cell Immunity.
Frontiers in immunology
Araujo Furlan CL,Tosello Boari J,Rodriguez C,Canale FP,Fiocca Vernengo F,Boccardo S,Beccaria CG,Adoue 💷 V,Joffre O,Gruppi A,Montes CL,Acosta Rodriguez EV
45-5825 was used in Flow cytometry/Cell sorting to study the role of regulatory T cells 💷 during Trypanosoma cruzi infection.
Thu Sep 26 00:00:00 EDT 2024
The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection.
Immunology
Gonçalves AC,Ferreira 💷 LS,Manente FA,de Faria CMQG,Polesi MC,de Andrade CR,Zamboni DS,Carlos IZ
45-5825 was used in Flow cytometry/Cell sorting to indicate that the NLRP3 💷 inflammasome contributes to protecion against infection from S. schenckii by linking the innate recognition of S. schenckii to the adaptive 💷 immune response.
Thu Jun 01 00:00:00 EDT 2024
Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged 💷 APP SWE /PS1 ΔE9 murine model of Alzheimer's disease.
Scientific reports
Minter MR,Hinterleitner R,Meisel M,Zhang C,Leone V,Zhang X,Oyler-Castrillo P,Zhang X,Musch MW,Shen X,Jabri 💷 B,Chang EB,Tanzi RE,Sisodia SS
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue Sep 05 00:00:00 EDT 2024
Conventional 💷 NK cells and ILC1 are partially ablated in the livers of Ncr1 iCreTbx21 fl/fl mice.
Wellcome open research
Cuff AO,Male V
Published figure 💷 using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Sat Jan 09 00:00:00 EST 2024
Resistance to TGFβ suppression and improved 💷 anti-tumor responses in CD8+ T cells lacking PTPN22.
Nature communications
Brownlie RJ,Garcia C,Ravasz M,Zehn D,Salmond RJ,Zamoyska R
Published figure using T-bet monoclonal antibody 💷 (Product # 45-5825-82) in Flow Cytometry
Tue Nov 07 00:00:00 EST 2024
CD36 receptor regulates malaria-induced immune responses primarily at early blood 💷 stage infection contributing to parasitemia control and resistance to mortality.
The Journal of biological chemistry
Thylur RP,Wu X,Gowda NM,Punnath K,Neelgund SE,Febbraio M,Gowda 💷 DC
Fri Jun 02 00:00:00 EDT 2024
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Cell
Clever D,Roychoudhuri R,Constantinides MG,Askenase MH,Sukumar 💷 M,Klebanoff CA,Eil RL,Hickman HD,Yu Z,Pan JH,Palmer DC,Phan AT,Goulding J,Gattinoni L,Goldrath AW,Belkaid Y,Restifo NP
Published figure using T-bet monoclonal antibody (Product # 💷 45-5825-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2024
B-cell anergy induces a Th17 shift in a novel B lymphocyte transgenic 💷 NOD mouse model, the 116C-NOD mouse.
European journal of immunology
Carrascal J,Carrillo J,Arpa B,Egia-Mendikute L,Rosell-Mases E,Pujol-Autonell I,Planas R,Mora C,Mauricio D,Ampudia RM,Vives-Pi M,Verdaguer 💷 J
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2024
Human Head and Neck 💷 Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
Journal of immunology (Baltimore, Md. : 1950)
Younis RH,Han KL,Webb TJ
Published 💷 figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2024
CXCL16-positive dendritic cells enhance invariant 💷 natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
45-5825 was used in Flow cytometry/Cell sorting to study 💷 the co-stimulatory role of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer T (iNKT) cell activation and tumour control, showing that 💷 CXCL16-positive dendritic cells enhance iNKT cell-dependent IFNγ production and tumor control.
Wed Jun 01 00:00:00 EDT 2024
IL12-mediated sensitizing of T-cell receptor-dependent 💷 and -independent tumor cell killing.
Oncoimmunology
Braun M,Ress ML,Yoo YE,Scholz CJ,Eyrich M,Schlegel PG,Wölfl M
45-5825 was used in Flow cytometry/Cell sorting to investigate 💷 how IL12, and other inflammatory cytokines, shape effector functions of human T-cells.
Fri Jul 01 00:00:00 EDT 2024
The transduction pattern of 💷 IL-12-encoding lentiviral vectors shapes the immunological outcome.
European journal of immunology
Goyvaerts C,Broos K,Escors D,Heirman C,Raes G,De Baetselier P,Thielemans K,Breckpot K
Published figure 💷 using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2024
The MAPK-Activated Kinase MK2 Attenuates Dendritic 💷 Cell-Mediated Th1 Differentiation and Autoimmune Encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Soukup K,Halfmann A,Le Bras M,Sahin E,Vittori S,Poyer F,Schuh C,Luger 💷 R,Niederreiter B,Haider T,Stoiber D,Blüml S,Schabbauer G,Kotlyarov A,Gaestel M,Felzmann T,Dohnal AM
45-5825 was used in Flow cytometry/Cell sorting to investigate the role 💷 of MK2 in dendritic cells, showing that it attenuates dendritic cell-mediated Th1 differentiation and autoimmune encephalomyelitis.
Wed Jul 15 00:00:00 EDT 💷 2024
Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy.
Journal of immunology (Baltimore, Md. 💷 : 1950)
Rasouli J,Ciric B,Imitola J,Gonnella P,Hwang D,Mahajan K,Mari ER,Safavi F,Leist TP,Zhang GX,Rostami A
45-5825 was used in Flow cytometry/Cell sorting to 💷 characterise GM-CSF production by T cells of MS patients and to determine the effect of IFN-β therapy on its production.
Mon 💷 Jun 01 00:00:00 EDT 2024
Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3.
PloS one
Deng YQ,Yang 💷 YQ,Wang SB,Li F,Liu MZ,Hua QQ,Tao ZZ
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue May 31 00:00:00 💷 EDT 2024
Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T 💷 cells in tumors.
Oncotarget
Colbeck EJ,Hindley JP,Smart K,Jones E,Bloom A,Bridgeman H,McPherson RC,Turner DG,Ladell K,Price DA,O'Connor RA,Anderton SM,Godkin AJ,Gallimore AM
45-5825 was used in 💷 Flow cytometry/Cell sorting to study the enrichment of tumor-infiltrating Treg populations and assess the role of IL-2 in pertubation of 💷 Treg frequencies in tumors.
Tue Sep 22 00:00:00 EDT 2024
IL-10 inhibits neuraminidase-activated TGF-β and facilitates Th1 phenotype during early phase of 💷 infection.
Nature communications
Dutta A,Huang CT,Chen TC,Lin CY,Chiu CH,Lin YC,Chang CS,He YC
45-5825 was used in Flow cytometry/Cell sorting to reveal a previously 💷 unrecognized function of Th1 cell-derived IL-10 in vivo.
Mon Mar 02 00:00:00 EST 2024
Chronic Trichuris muris Infection Decreases Diversity of the 💷 Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli.
PloS one
Holm JB,Sorobetea D,Kiilerich P,Ramayo-Caldas Y,Estellé J,Ma T,Madsen L,Kristiansen K,Svensson-Frej M
45-5825 was 💷 used in Flow cytometry/Cell sorting to study the influence of chronic parasite infection on the intestinal microbiota and the adaptive 💷 immune system.
Wed Feb 03 00:00:00 EST 2024
MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung.
The Journal of allergy 💷 and clinical immunology
Malmhäll C,Alawieh S,Lu Y,Sjöstrand M,Bossios A,Eldh M,Rådinger M
45-5825 was used in Flow cytometry/Cell sorting to investigate the contribution 💷 of microRNA-155 to TH2-mediated allergen-induced airway inflammation in a mouse model.
Thu May 01 00:00:00 EDT 2014
CD4CD8αα lymphocytes, a novel human 💷 regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease.
PLoS biology
Sarrabayrouse G,Bossard C,Chauvin JM,Jarry 💷 A,Meurette G,Quévrain E,Bridonneau C,Preisser L,Asehnoune K,Labarrière N,Altare F,Sokol H,Jotereau F
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow 💷 Cytometry
Tue Apr 01 00:00:00 EDT 2014
High eomesodermin expression among CD57+ CD8+ T cells identifies a CD8+ T cell subset associated 💷 with viral control during chronic human immunodeficiency virus infection.
Journal of virology
Simonetta F,Hua S,Lécuroux C,Gérard S,Boufassa F,Sáez-Cirión A,Pancino G,Goujard C,Lambotte O,Venet 💷 A,Bourgeois C
45-5825 was used in Flow cytometry/Cell sorting to investigate the phenotype of CD57-expressing CD8(+) T cells in healthy donors 💷 and during HIV infection combining CD57 expression to Eomesodermin.
Wed Oct 01 00:00:00 EDT 2014
Prophylaxis with a respiratory syncytial virus (RSV) 💷 anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice.
Journal 💷 of virology
Boyoglu-Barnum S,Chirkova T,Todd SO,Barnum TR,Gaston KA,Jorquera P,Haynes LM,Tripp RA,Moore ML,Anderson LJ
45-5825 was used in Flow cytometry/Cell sorting to suggest 💷 that the RSV G protein not only contributes to disease, but also dampens the host immune response to infection.
Mon Sep 💷 01 00:00:00 EDT 2014
T cell factor-1 controls the lifetime of CD4+ CD8+ thymocytes in vivo and distal T cell receptor 💷 α-chain rearrangement required for NKT cell development.
PloS one
Sharma A,Berga-Bolaños R,Sen JM
45-5825 was used in Flow cytometry/Cell sorting to demonstrate that 💷 T cell factor-1, encoded by the Tcf7 gene, is critical for the extended lifetime of double positive thymocytes.
Fri Apr 29 💷 00:00:00 EDT 2024
Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells.
Journal 💷 of immunology (Baltimore, Md. : 1950)
McCarthy NE,Bashir Z,Vossenkämper A,Hedin CR,Giles EM,Bhattacharjee S,Brown SG,Sanders TJ,Whelan K,MacDonald TT,Lindsay JO,Stagg AJ
45-5825 was used 💷 in Flow cytometry/Cell sorting to characterise a novel subset of human Vδ2T cells that populate the human intestinal mucosa and 💷 contribute to mucosal inflammation.
Sun Sep 01 00:00:00 EDT 2013
Helicobacter pylori infection in a pig model is dominated by Th1 and 💷 cytotoxic CD8+ T cell responses.
Infection and immunity
Kronsteiner B,Bassaganya-Riera J,Philipson C,Viladomiu M,Carbo A,Pedragosa M,Vento S,Hontecillas R
45-5825 was used in Flow cytometry/Cell 💷 sorting to investigate the phenotypic and functional changes in PMBC populations during Helicobacter pylori infection, showing that infection is dominated 💷 by Th1 and cytotoxic CD8+ T cell responses.
Tue Oct 01 00:00:00 EDT 2013
Alterations in regulatory T cells induced by specific 💷 oligosaccharides improve vaccine responsiveness in mice.
PloS one
Schijf MA,Kerperien J,Bastiaans J,Szklany K,Meerding J,Hofman G,Boon L,van Wijk F,Garssen J,Van't Land B
45-5825 was 💷 used in Flow cytometry/Cell sorting to identify factors affecting the quality of the immune response to vaccination.
Tue May 27 00:00:00 💷 EDT 2014
Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells.
Journal of immunology (Baltimore, Md. 💷 : 1950)
Chang PP,Lee SK,Hu X,Davey G,Duan G,Cho JH,Karupiah G,Sprent J,Heath WR,Bertram EM,Vinuesa CG
45-5825 was used in Flow cytometry/Cell sorting to 💷 identify a novel mechanism that affects the distribution of self-reactive cytotoxic effector cells.
Sun Jul 15 00:00:00 EDT 2012
DOCK8 deficiency impairs 💷 CD8 T cell survival and function in humans and mice.
The Journal of experimental medicine
Randall KL,Chan SS,Ma CS,Fung I,Mei Y,Yabas M,Tan 💷 A,Arkwright PD,Al Suwairi W,Lugo Reyes SO,Yamazaki-Nakashimada MA,Garcia-Cruz Mde L,Smart JM,Picard C,Okada S,Jouanguy E,Casanova JL,Lambe T,Cornall RJ,Russell S,Oliaro J,Tangye SG,Bertram EM,Goodnow 💷 CC
45-5825 was used in Flow cytometry/Cell sorting to study the role of DOCK8 in the survival and function of human 💷 and mouse CD8 T cells.
Mon Oct 24 00:00:00 EDT 2011
CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells 💷 to program cytotoxic Th1 differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Qui HZ,Hagymasi AT,Bandyopadhyay S,St Rose MC,Ramanarasimhaiah R,Ménoret A,Mittler RS,Gordon SM,Reiner 💷 SL,Vella AT,Adler AJ
Published figure using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2011
Increase in 💷 Th17 and T-reg lymphocytes and decrease of IL22 correlate with the recovery phase of acute EAE in rat.
PloS one
Almolda B,Costa 💷 M,Montoya M,González B,Castellano B
Mon Mar 26 00:00:00 EDT 2012
Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT 💷 and conventional T cells.
PloS one
Yabas M,Godfrey DI,Goodnow CC,Hoyne GF
45-5825 was used in Flow cytometry/Cell sorting to investigate the effect of 💷 mutations in heterogeneous ribonucleoprotein L-like protein on NKT and T cells.
Mon Mar 26 00:00:00 EDT 2012
Cytokine requirements for the differentiation 💷 and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Ness-Schwickerath KJ,Jin C,Morita CT
Published figure 💷 using T-bet monoclonal antibody (Product # 45-5825-82) in Flow Cytometry
Tue Jun 15 00:00:00 EDT 2010
